Abstract submitted for the British Thoracic Winter Meeting 2015 conference presentation
10,813 patients with a diagnosis of Chronic Obstructive Pulmonary Disease (COPD), identified from the Hampshire Health Record analytical database, were followed for three years. The main outcomes measured were death and the respiratory-caused hospitalisation rate. A multivariate cox regression model was used to calculate survival risk. It produced relative risks (RR) and confidence intervals (CI) adjusted for age, gender, smoking status and %FEV1.
The results showed significant variation in patient outcome. It demonstrated that underweight COPD patients have the worst outcomes, whilst being overweight or obese appears to have protective effects. This reinforces the importance of nutritional supplementation in underweight COPD patients, whilst further research into the obesity paradox seen in COPD is required.